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Jamie Metzl
Technology and Healthcare Futurist, Global Affairs Specialist, Science Fiction Novelist, and Genetic Engineering Expert
Jamie Metzl is one of the world's leading futurists and global public health experts who has been called "the original Covid-19 whistleblower" for his groundbreaking work exploring pandemic origins. He is the author of five books, including recent bestseller Hacking Darwin: Genetic Engineering and the Future of Humanity.
Bio
Jamie Metzl is one of the world’s leading technology and healthcare futurists and strategists, Founder and Chair of the global social movement OneShared.World, a Senior Fellow of the Atlantic Council, a faculty member of NextMed Health, and a Singularity University expert. He appears regularly on national and international media and his syndicated columns, podcasts, and interviews on AI, science, technology, and global affairs have reached hundreds of millions of people across the globe. Jamie is the author of seven books, including Superconvergence: How the Genetics, Biotech and AI Revolutions Will Transform Our Lives, Work, and World, Hacking Darwin: Genetic Engineering and the Future of Humanity, The AI Ten Commandments: A New Moral Code for Humanity, and the sci-fi thrillers Genesis Code and Eternal Sonata. In 2026, Jamie was appointed as a Commissioner of The Lancet Commission on Precision Health, which will develop a definitive framework for the future of technology-enhanced healthcare. He previously served in the U.S. National Security Council, State Department, and Senate Foreign Relations Committee, with the United Nations in Cambodia, and on the World Health Organization expert advisory committee on human genome editing. A former partner in a global private equity firm, he sits on advisory boards for multiple biotechnology and other companies and co-established the WisdomTree BioRevolution Exchange Traded Fund. Jamie holds a Ph.D. from Oxford, a law degree from Harvard, and an undergraduate degree from Brown and is an avid ironman triathlete and ultramarathon runner.
Keynotes
Featured Keynote
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Superconvergence: How the AI, Genetics, and Biotechnology Revolutions Will Transform Our Lives, Work, and World
The rapid growth of new AI systems like ChatGPT and Google Gemini has helped us recognize that profound change is on the horizon. Although many of us still think of these capabilities as little more than improved internet search tools, the implications are far deeper. Like the agricultural, industrial, and computer revolutions before it, the AI revolution will transform nearly every aspect of how we live and work, including our economies, our healthcare, the food we eat, and our interactions with the world around us. In this visionary, far-reaching, and highly practical talk, leading futurist and bestselling author of Superconvergence, Hacking Darwin, and The AI Ten Commandments, Jamie Metzl explores the big-picture implications of this transformative moment in history when we are rapidly increasing our ability to engineer intelligence and re-engineer biology—and shows how individuals, organizations, and societies can ride this wave of change rather than be overwhelmed by it.
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The End of Reactive Medicine: How AI and Other New Technologies are Powering Predictive and Preventive Health
The End of Reactive Medicine: How AI and Other New Technologies are Powering Predictive and Preventive Health
For centuries, healthcare has been reactive. We waited for people to get sick, then tried—often heroically—to save them. That era is now ending. Medicine is already shifting from one-size-fits-all treatment to precision healthcare shaped by each person’s unique biology. Genome sequencing, targeted cancer therapies, and data-driven diagnostics are already delivering extraordinary results. But as generative AI and exponential computing power converge with genomics, biotechnology, and vast health datasets, medicine is moving beyond precision toward predictive and preventive care models in which we can anticipate risk, intervene early, and keep people well before symptoms appear. In this fast-paced, visionary, and deeply practical keynote, technology and healthcare futurist Jamie Metzl, Commissioner of the Lancet Commission on Precision Health, takes audiences inside the next healthcare revolution and shows how AI and other new capabilities are transforming disease detection, drug development, care delivery, and health economics, and what it will take for leaders to thrive as prediction, prevention, and personalization redefine healthcare success.
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Artificial Intelligence, Human Creativity, and Our New Age of Spiritual Machines
Artificial Intelligence, Human Creativity, and Our New Age of Spiritual Machines
Whether we’re ready or not, artificial intelligence is set to transform nearly every dimension of human life, including how we work, live, create art, find meaning, and build communities of belief. Just as agriculture reshaped human civilization and seeded new faith traditions and the printing press fractured old authorities while giving rise to new ones, AI is now triggering the next great shift in how we understand ourselves and our place in the unfolding human story. In this mind-opening journey through deep history and near-future possibility, leading futurist, sci-fi novelist, and author of The AI Ten Commandments Jamie Metzl explores what happens—and how we can thrive—when our most powerful technologies begin to touch the most human questions: Who are we? What do we owe one another? And what does it mean to create, to believe, and to belong in an age of highly creative, and potentially even spiritual, machines? This keynote helps leaders, creators, and organizations understand not just what AI can do, but how we can strengthen human meaning, creativity, and values as intelligent machines increasingly shape our lives and societies.
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Beyond the Blue Zones: What the Revolutionary Science of Human Life Extension Means for You
Beyond the Blue Zones: What the Revolutionary Science of Human Life Extension Means for You
Most people know the basics of healthy longevity: exercise, good nutrition, meaningful relationships, and stress reduction. But revolutionary advances in biology, genetics, and artificial intelligence are now creating unprecedented opportunities to extend healthy human life beyond what was once considered possible, and unlocking new potential for health, productivity, and human flourishing in ways our ancestors could never have imagined. In this eye-opening and highly practical keynote, leading technology and healthcare futurist (and ultramarathoner) Jamie Metzl explores the latest breakthroughs in longevity science and what they mean for individuals, businesses, and governments. He explains how these advances could deliver more of life’s most precious resource—time—and why they will fundamentally reshape healthcare systems, economies, social structures, and public policy sooner than most people expect. This talk offers a clear framework for how leaders can prepare now for a future in which longer, healthier lives transform how we live and work, and even how our societies are organized.
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Optimizing Your Health in an Age of Exponential Technology
Optimizing Your Health in an Age of Exponential Technology
While many people feel overwhelmed by a flood of unscientific health claims and exaggerated promises about “hacking” aging or living forever, the converging revolutions in artificial intelligence, genetics, and biotechnology are delivering something far more powerful: real scientific insights into prevention, prediction, and long-term health with meaningful implications for every one of us. In this affirming, optimistic, and highly practical keynote, leading technology and healthcare futurist Jamie Metzl—who has completed 60 marathons, 40 ultramarathons, and 13 Ironman triathlons—explores how individuals can use today’s best science, not hype, to optimize their health and position themselves to benefit from the next generation of predictive and preventive medicine. This talk offers a clear, empowering framework for living healthier, more resilient lives in a world of rapidly accelerating technological change.
Since a “pause” on the development of artificial intelligence is a non-starter, we should devote our resources to preparing for the social and economic displacements that we know are coming. The key will be to let AIs and humans each do what they do best, and to figure out how AI and humans can best work together on everything else.
Q&A Interview with Jamie Metzl: We need a global OS upgrade
In this Q&A, leading technology and healthcare futurist Jamie Metzl discusses a range of topics and trend lines that will unfold over the next several decades: whether a version of Moore's Law applies to genetic technologies, the ethics of genetic engineering, the dangers of gene hacking, the end of sex, and much more.
The Future, According to Jamie Metzl
In a coffee shop near New York's Central Park, where Metzl trains for ultramarathons, Brunswick Partner Raul Damas talked with Jamie about the next stage of human reproduction, and why storytelling can help leaders of business prepare for a radically transformed future.
The Metaverse Could Become an Oppressive Dystopia. It Needs a Congress.
Jamie shares his insights on how since the future of the Metaverse is not predetermined, the difference between these utopian and dystopian futures is still up for grabs.
Stifling debate on the virus makes another one more likely
A number of people have asked whether the recent increase in attention to the pandemic origins has felt like vindication for the small number of us who have been pushing against the tide since early last year by raising essential questions challenging the dominant narrative and calling for a full investigation into all credible hypotheses. The answer is not really or, perhaps, not yet. Our goal is not attention or media interviews but a full investigation, with China's involvement if at all possible but without that if not, to help us understand what went wrong and address our greatest vulnerabilities.
As the pandemic rages on, we must demand accountability from the World Health Assembly
You may have never heard of the World Health Assembly, an annual meeting of health ministers from around the world that opens Monday, but your safety and that of future generations may well depend on what happens in this previously obscure international gathering.
What happened in Wuhan? Why questions still linger on the origin of the coronavirus
A lack of transparency from Chinese officials and looming geopolitical consequences have damaged the credibility of a WHO-led inquiry into how the virus that causes COVID-19 originated. Lesley Stahl reports.
Miraculous mRNA Vaccines are only the Beginning | Opinion
The Pfizer and Moderna mRNA vaccines now being administered across the United States and the globe aren't just providing the first glimmers of hope in our struggle against COVID-19. They are also offering an early look at how the miraculous tools of the genetics revolution will transform our health care and our world over the coming years. But unless we can develop better ways to reap the great benefits while avoiding the potential harms of our Promethean technologies, our moment of triumph could set us on a path to disaster.
Assembly keynote speaker says ministry must help lay right foundation for nation's rebuilding
Futurist Jamie Metzl says systemic reform is needed to protect the most vulnerable
OneShared.World Seeks a New Global Operating System
Like the prophets of old, Jamie Metzl bemoans a world wracked by oppression, destruction, poverty and social injustice. This March, as the coronavirus spread its furious tentacles across the world, Metzl had a revelation...
OneShared. World Seeks a New Global Operating System
Published in Hadassah Magazine, September 2020, Jamie's article starts with his revelation, “I realized that our biggest problems are global—but the way we are organized is national."
Think this coronavirus crisis is bad? The next could be worse — if we don't act now
As the coronavirus pandemic, today grows ever-more dangerous, we must not only rise to meet this crisis but also step up our efforts to prepare for even more dangerous pathogens — either naturally emerging or synthetically engineered — that are very likely to follow.
Covid-19 offers a chance to build a better world. We must seize it.
(CNN)The coronavirus alone didn't itself break our world. It just exposed a world that was already breaking.
Polymath Jamie Metzl on AI, Genetics, and the Future
Where humanity is heading from a tech futurist and geopolitical expert's view.
Jamie Metzl on the Future of Genetics – The Joe Rogan Experience MAY 21, 2019
People have been manipulating life for a very long time and our power to manipulate it will only continue to grow. “Our model of what is normal is just going to change”
His new book "Hacking Darwin" is available...Jamie Metzl by The Joe Rogan May 10, 2019 Experience
Podcast with Joe Rogan on Jamie's new book, "Hacking Darwin."
Ten steps to prepare for an exponential future
1. Do what you can to preserve your youth 2. Quantify and monitor your health 3. Freeze your essential biological materials 4.If you plan on ever having children, freeze your eggs or your sperm 5.Manage your public identity 6.Learn the language of code 7.Become multicultural 8.Become an obsessive learner 9.Invest in physical community 10. Don't get stuck in today
Polymath Jamie Metzl on AI, Genetics, and the Future
Where humanity is heading from a tech futurist and geopolitical expert's view.
Ten steps to prepare for an exponential future
It took around 12,000 years to move from the agrarian to the industrial revolution but only a couple of hundred years to go from the industrial to the information revolution that's now propelling us in a short number of decades into the artificial intelligence revolution.
Profile of Jamie from Psychology Today
Kim Jong Un Has No Intention of Giving Up His Nukes
Kim Jong Un has no intention of giving up his nukes.
Donald Trump and Kim Jong Un, Made for Each Other?
Jamie Metzl, a senior fellow of the Atlantic Council, has served as a director on the US National Security Council, at the State Department and on the Senate Foreign Relations Committee staff. He also served with the United Nations in Cambodia and is author of "Eternal Sonata" and three other books. The views expressed in this commentary are his own.
Trump Has Made a Bad North Korea Situation Even Worse
North Korea's Kim is less constrained by his government institutions than is Trump, but we do not yet fully know how effectively America's governance culture and institutions can moderate the dangerous, destabilizing, and mercurial impulses of the US President.
A Modern Day Renaissance Man Shares Lessons On Happiness, Habits, And Health
This Huffington Post interview with Jamie went viral and even inspired a new musical score based on its themes
Homo Sapiens 2.0: We Need a Species-Wide Conversation on the Future of Human Genetic Engineering
After 4 billion years of evolution by one set of rules, our species is about to begin evolving by another. Overlapping and mutually reinforcing revolutions in genetics, information technology, artificial intelligence, big data analytics, and other fields are providing the tools that will make it possible to genetically alter our future offspring should we choose to do so. For some very good reasons, we will. As the genetic revolution plays out, it will raise fundamental questions about what it means to be human, unleash deep divisions within and between groups, and could even lead to destabilizing international conflict..
It's Time for the United States to Talk About Genetics
This Washington Post editorial calls for a wide-ranging and structured national and international dialogue on the rapidly unfolding genetics revolution
The Revolution in DNA Science -- And What To Do About It
In the Twilight Rise Up Monsters: Why the Trump Foreign Policy Undermines US and World Security
The United States is facing perhaps the most dangerous moment since the 1941 Pearl Harbor attack or the 1962 Cuban Missile Crisis. This danger does not stem from terrorism, immigration, or Islamic extremism but instead from the rapid deterioration of the post-World War Two international order. The Trump administration did not create this crisis but is contributing to it massively. Unless this changes, the ensuing conflict will likely destabilize the world and undermine America’s security.
Uncovering a Global Health Conspiracy in Jamie Metzl's Near-Future Thriller
Interview with WNYC's Leonard Lopate
The Coming Collapse of North Korea
Those predicting North Korea's imminent collapse have continually been proven wrong. But today, the North Korean madness may well be nearing its endgame.
- 2026 The AI Ten Commandments: A New Moral Code for Humanity
- 2024 Superconvergence: How the Genetics, Biotech, and AI Revolutions will Transform Our Lives, Work, and World
- 2019 Hacking Darwin: Genetic Engineering and the Future of Humanity
- 2017 Homo Sapiens 2.0: We need a species-wide conversation about the future of human genetic enhancement
- 2016 Eternal Sonata
- 2014 Genesis Code
- 2004 The Depths of the Sea
- 1997 Western Responses to Human Rights Abuses in Cambodia
Jamie's fabulous presentation on genetic engineering – past, present and future -- was at once thought provoking, inspiring, frightening and enlightening. It was simply the best presentation I ever have heard in all my 71 years. I look forward to the publication of Hacking Darwin and can't wait to get my hands on it.
David Parker - Board Member, Brown University Hillel
“A page-turning journey through space and time that shows us how our lives will be changed by imminent technological advances we once only dreamed of.”
David Sinclair, Professor of Genetics, Harvard Medical School, and author of Lifespan: Why We Age―and Why We Don't Have To
“San Jose State thinks a great deal these days about how to approach healthcare studies with our students, how that interacts with technology and the humanities, and the complexity of programs we need to create that will allow us to think differently about our place in an ever changing world, as well as how we can have a positive impact. At our event, Jamie was exceptionally engaged with the students, and in both sessions before the lecture, everyone one came up with him afterwards to talk further with him. He offered thoughtful insights into these issues in an engaging, entertaining way that I know is going to generate a great deal of discussion and debate among our students and staff. He reminded us that the future is already here and we should engage with it actively and in the spirit of our values”
Dr. Mary A. Papazian, President, San Jose State University
I was fortunate to host Jamie for both a small group dinner with several high value clients and then have Jamie present for 30 minutes followed by a 45 minute fireside discussion at our firm's annual Macro Conference with over 250 attendees. I can say Jamie's depth and breadth of knowledge about biology, history, genomics., AI/technology, biotechnology, agriculture, and food is astounding with instant recall. Additionally, his time spent with our government and other major global organizations provided him with broad and excellent real world know-how not just theory in how we can leverage these technologies and end goals to improve the US and world at large. Jamie engaged the small group at dinner who were also fascinated with how he leveraged AI to help draft his science fiction novel. We also covered a lot of ground on man+machine vs. man against machine and how we can leverage our best skills with targeted roles and goals for AI to improve and expedite the process. So we won't be replaced by machines. At our conference with our larger group Jamie walked through the history and natural 'genomics' process and how AI and biotechnology can accelerate that to move us from general healthcare to predictive medicine was fascinating. We covered his role in the Covid lab leak vs. wet market and how we can leverage mRNA technology for so many health issues along with CRISPR and cell genomics. But, aside from Jamie being a great speaker and storyteller to engage the audience, he is also a wonderful person and a pleasure to spend time with in discussion about anything frankly. In preparation for our event I read Superconvergence and am now about to tackle Hacking Darwin, his earlier book. I hope that our paths will cross again in the near future.
Investment Banking Client
“Provocative, challenging, wonderful, exciting and a bit scary are just a sampling of the reactions from the nearly 1500 attendees at Jamie Metzl's talks we hosted in advance of the debut of his book Hacking Darwin: Genetic Engineering and the Future of Humanity. Jamie's fast pace and vast knowledge kept audiences of all ages and persuasions locked on.”
John Carney, CEO, Center for Practical Bioethics
We invited Jamie to give a keynote address to 500 doctors at a major medical convention. His brilliant talk simply blew people's minds and made them think differently about where medicine is heading and what that means for all of us. With tremendous thoughtfulness, energy, creativity, and skill, Jamie helped participants imagine how they might ride the wave of exponential change toward greater success rather than be crushed by it. The positive response was overwhelming. Jamie is a superstar.
Joshua Abram, Co-Founder and CEO, TMRW Life Sciences
- "If you can only read one book on the future of our species, this is it." - Sanjay Gupta - "a must-read book." - Siddhartha Mukherjee - "an outstanding guide to the most important conversation of our lives." - Ray Kurzweil - "an intellectual masterbatortium-at once stimulating and consummately satisfying." - Dan Buettner - "important and thought-provoking." - George Church - "a critical journey through opportunities and obstacles on humanity's greatest expedition: the exploration and re-imagining of what it means to be human." – Mayor Eric Garcetti - "essential reading if you want to understand what will be seen as the most important thing happening in this epoch." - Richard A. Clarke
Praise for Jamie's book Hacking Darwin: Genetic Engineering and the Future of Humanity
“During the 25 years I have known Jamie Metzl, he has always been ahead of the curve. There is no one better to help us understand and prepare for the fast approaching technological revolutions. Superconvergence is brilliant. I can't recommend it more strongly.”
Sanjay Gupta MD, bestseller author, neurosurgeon, and Emmy-award winning chief medical correspondent (CNN)
“In Superconvergence, Jamie Metzl takes readers on a magical journey through the science of the intersecting genetics, biotech, and AI revolutions, deeply explores the implications, and challenges us to think creatively and proactively about what comes next. Very few books are absolute must-reads. This is one.”
Siddhartha Mukherjee, assistant professor of medicine at Columbia University and author of The Gene: An Intimate History
“Jamie was the closing keynote at our global CEO conference. He had an uncanny way tying together all of the themes from the previous sessions, into a masterful and thought provoking closing. No canned script, no death by PowerPoint, but an engaging, entertaining and intelligent talk worthy of our audience. Jamie's keynote had the energy and enthusiasm of a rock star, and left our audience wanting more. I would most certainly book Jamie again for another YPO event!”
Stephen Forte, President, Silicon Valley YPO
Jamie Metzl is one of America's foremost experts on China. His captivating presentation at the Vail Symposium provided the story behind the headlines and walked deftly the audience through the amazing complexity of China's economic transition. The mark of a truly great speaker is being able to present a complicated topic in a way the audience can understand and absorb. Jamie's brilliant talk explained the difficult choices China's leaders face as they struggle to move their economy to a new development phase and maintain growth in extremely challenging circumstances. It's hard to imagine a better or more engaging speaker on China's economy, politics, and geopolitics than Jamie Metzl.
Attendee, Vail Symposium
Jamie is a fantastic authority and resource on all things related to China. I hired Jamie as a panelist and keynote speaker in 2016 after hearing Jamie speak at an Atlantic Council event. He was extremely knowledgeable, flexible and a pleasure to work with on our event programming. I was particularly impressed by Jamie's presence and command of the topics and his ability to engage with the engage the audience in a meaningful way. Throughout our preparation, Jamie was always accessible and provided constructive ways to improve our program. Jamie is at the top of my list for my speaking engagements needs.
Terrence J. Richardson, Head of Corporate & Investment Bank Marketing, HSBC Bank
Dr. Jamie Metzl spoke to a captivated audience about a fascinating and complicated subject. Bio-engineering and its impact upon the future of mankind was the topic Dr. Metzl aptly articulated in an enthralling yet relatable style. From the start, he built a genuine rapport with the audience as he communicated so that each person understood as clearly as possible the subject matter. Jamie’s presentation was amazingly fluid and perfectly paced as he spoke effortlessly without notes or prompts. “Jamie is the best speaker we’ve ever had.” “This event was a home run because of Jamie Metzl!” “Jamie is engaging and smoothly breaks it down.” These are just a few samples of the positive comments received from the audience after the presentation. Our community is excited about Jamie’s return for an encore!
Trudy Jacobson, Jewish Federation of Greater Kansas City
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