Simon Luthi Former Fortune 100 Executive at JPMorgan Chase and American Express; Bestselling Author of "Becoming the Rocket Shaman"; Creator of Transmutation Design™

The Science and Practice of Upgrading the Human Operating System

Most high performers are trying to run better apps on a phone that is overheating, out of storage, and running on three percent battery. No amount of productivity hacking, biohacking, or executive coaching will fix that. You do not need a better app. You need a new operating system.

Simon introduces Transmutation Design™, the three-phase methodology he developed after transforming from a burned-out Fortune 100 executive into a regulated, high-performing leader with biomarker data to prove it.

Audiences learn how to use HRV data to read their nervous system like a dashboard, how continuous glucose monitoring reveals invisible stress, and how the Rewrite Your Story™ process breaks patterns that keep leaders stuck.

This is the talk for organizations ready to move from awareness to action.

What Audiences Walk Away With:

• The three-phase Transmutation Design™ framework: Reveal, Recode, Regenerate
• Practical nervous system regulation techniques for high-stakes moments
• How to measure leadership performance through biomarkers
• The Rewrite Your Story™ approach to breaking survival patterns

Why Dysregulation, Not Incompetence, Is the Hidden Risk No Board Is Measuring

Think about the most impressive leader you have ever worked for. The one who hit the biggest numbers, made the fastest decisions, and radiated pressure like a force of nature.

Now ask yourself how it felt to be in the room with that person.

The most dangerous leader in any organization is not the least experienced or the least intelligent. It is the most dysregulated. The one flooding every room with the biochemical equivalent of a five-alarm fire while believing they are performing at their best.

Simon draws on his journey from the C-suite to the cancer ward to the stage and makes the counterintuitive case that in a post-AI world, a leader's competitive advantage is no longer intelligence. It is their nervous system.

Backed by real biomarker data and delivered with the authority of someone who has lived both sides of this equation.

What Audiences Walk Away With:

• A new definition of leadership risk beyond strategy and competence
• Understanding of how dysregulated leaders create toxic environments invisibly
• The case for nervous system regulation as a measurable leadership competency
• Awareness that the AI era demands a fundamentally different kind of leader