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Simon Luthi

Former Fortune 100 Executive at JPMorgan Chase and American Express; Bestselling Author of "Becoming the Rocket Shaman"; Creator of Transmutation Design™

Simon Luthi is a former Fortune 100 executive (Chief Strategy Officer at JPMorgan Chase, Head of Product at American Express) who helped scale Chase Travel from $2B to $10B. After a cancer diagnosis, he created Transmutation Design™, helping executives upgrade their human operating system for the AI era.

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Bio

Simon Luthi is a former Fortune 100 executive who served as Chief Strategy Officer at JPMorgan Chase and Head of Product at American Express. Today he is a bestselling and award-winning author, keynote speaker, and creator of Transmutation Design™. After helping scale Chase Travel from $2 billion to $10 billion, a cancer diagnosis forced him to confront a truth most leaders ignore: in the AI era, leadership failure is often a biology problem, not a strategy problem.

Today, Simon helps executives stay healthy, sharp, and sovereign in a post-AI world by teaching leaders how to upgrade their human operating system. His work blends neuroscience, leadership, and personal transformation to help individuals and organizations perform at a higher level in an increasingly complex world.

Simon is the author of Becoming the Rocket Shaman, a #1 Amazon New Release and winner of Best Personal Transformation Book of 2025. He is a global keynote speaker on neuroscience and leadership in the post-AI era and has been featured on CBS, FOX, NBC, and more than 100 media outlets.

Keynotes

Featured Keynote

  • Transmutation Design™: From Burned-Out to Brilliant
  • The Most Dangerous Leader in the Room
  • 2025 Becoming the Rocket Shaman - Lessons in Healing Chronic Illness, Emotional Pain, and Burnout When Nothing Else Works
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